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Canadian Breastfeeding Foundation

Domperidone Dosage Instructions for Induced Lactation

The maximum dose for domperidone is 20 mg 4 times per day. The suggested beginning dose is 10 mg 4 times per day for 1 week, then increasing to 20 mg 4 times per day. This should be increased gradually as per the instructions in the individual protocols. It is advisable to continue to take the domperidone from the initiation of lactation until weaning. Most mothers find that when they forget a dose their milk supply decreases. However, once lactation is well established and the baby is breastfeeding well, the mother may consider slowly decreasing the domperidone. If her milk supply drastically decreases, she can always increase the dose back to 20 mg 4 times per day.